|
|
cholesterol + reduced_ferredoxin_[iron-sulfur]_cluster + H+ + O2 <=> 27-Hydroxycholesterol + oxidized_ferredoxin + H2O
|
1.14.15.29
cholest-4-en-3-one 26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming]
|
–
|
|
|
BRENDA:
BS418546
MetaCyc:
RXN-17656
|
|
|
|
cholesterol + reduced_adrenodoxin + H+ + O2 <=> 27-Hydroxycholesterol + oxidized_ferredoxin + H2O
|
1.14.15.15
cholestanetriol 26-monooxygenase
|
–
|
K
|
|
BRENDA:
BS386397
KEGG:
R08505
|
|
|
|
27-Hydroxycholesterol + reduced_flavodoxin + O2 <=> 7alpha,27-dihydroxycholesterol + flavin + H2O
|
1.14.14.23
cholesterol 7alpha-monooxygenase
1.14.14.29
25/26-hydroxycholesterol 7alpha-hydroxylase
|
–
–
|
K
|
|
KEGG:
R07372
|
|
|
|
27-Hydroxycholesterol <=> solasodine
|
not assigned
|
–
|
|
|
KEGG:
R08506
|
|
|
|
27-Hydroxycholesterol <=> tomatidine
|
not assigned
|
–
|
|
|
KEGG:
R08507
|
|
|
|
27-Hydroxycholesterol <=> Solanidine
|
not assigned
|
–
|
|
|
KEGG:
R08508
|
|
|
|
27-Hydroxycholesterol + 2 O2 + 2 NADPH + 2 H+ <=> 5-cholestene-26-oic_acid-3beta-ol + 2 NADP+ + 3 H2O
|
not assigned
|
–
|
K
|
|
KEGG:
R08726
|
|
|
|
27-Hydroxycholesterol + reduced_ferredoxin_[iron-sulfur]_cluster + O2 + H+ <=> (25R)-26-oxocholesterol + oxidized_ferredoxin + H2O
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-17657
|
|
|
|
27-Hydroxycholesterol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (25R)-cholest-5-ene-3beta,7alpha,26-triol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.29
25/26-hydroxycholesterol 7alpha-hydroxylase
|
–
|
|
|
MetaCyc:
RXN-7981
|
|
|
|
27-Hydroxycholesterol + O2 <=> 26-Hydroxycholest-5-en-3-one + H2O2
|
1.1.3.6
cholesterol oxidase
|
–
|
|
|
BRENDA:
BS188857
|
|
|
|
27-Hydroxycholesterol + NADPH + H+ + O2 <=> 7alpha,27-dihydroxycholesterol + NADP+ + H2O
|
1.14.14.29
25/26-hydroxycholesterol 7alpha-hydroxylase
|
–
|
|
|
BRENDA:
BS375088
|
|
|
|
27-Hydroxycholesterol + NADPH + H+ + O2 <=> 3beta,7alpha-dihydroxy-5-cholestenoic_acid + NADP+ + H2O
|
1.14.14.29
25/26-hydroxycholesterol 7alpha-hydroxylase
|
–
|
|
|
BRENDA:
BS427296
|
|
|
|
UDP-glucose + 27-Hydroxycholesterol <=> UDP + a_sterol_27-beta-D-glucoside
|
2.4.1.B4
|
–
|
|
|
BRENDA:
BR49079
|
|